TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

Supplementation of magnesium (Mg2+) or its inclusion in biomaterials has beneficial effects for bone formation, but it has also been reported that it can have detrimental effects. Here, the authors analyse dose- and time-dependent effects of Mg2+ on bone regeneration and show that it can stimulate m...

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Bibliographic Details
Main Authors: Wei Qiao, Karen H. M. Wong, Jie Shen, Wenhao Wang, Jun Wu, Jinhua Li, Zhengjie Lin, Zetao Chen, Jukka P. Matinlinna, Yufeng Zheng, Shuilin Wu, Xuanyong Liu, Keng Po Lai, Zhuofan Chen, Yun Wah Lam, Kenneth M. C. Cheung, Kelvin W. K. Yeung
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23005-2

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