Genetic variants of <it>NOXA</it> and <it>MCL1</it> modify the risk of HPV16-associated squamous cell carcinoma of the head and neck

Genetic variants of <it>NOXA</it> and <it>MCL1</it> modify the risk of HPV16-associated squamous cell carcinoma of the head and neck

<p>Abstracts</p> <p>Background</p> <p>The cooperation between phorbol 12-myristate 13-acetate induced protein 1 (NOXA) and myeloid cell leukemia 1 (MCL1) is critical in the intrinsic apoptotic pathway. Human papillomavirus 16 (HPV16), by inducing p53 and pRb-E2F degrada...

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Bibliographic Details
Main Authors: Zhou Ziyuan, Sturgis Erich M, Liu Zhensheng, Wang Li-E, Wei Qingyi, Li Guojun
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Cancer
Subjects:
<it>NOXA</it>
<it>MCL1</it>
HPV16
Genetic susceptibility
Squamous cell carcinoma of the head and neck
Online Access:http://www.biomedcentral.com/1471-2407/12/159

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