Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study

The amyloid plaques are a key hallmark of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Amyloidogenesis is a complex long-lasting multiphase process starting with the formation of nuclei of amyloid peptides: a process assigned as a primary nucleation. Curcumin (CU)...

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Bibliographic Details
Main Authors: Irini Doytchinova, Mariyana Atanasova, Evdokiya Salamanova, Stefan Ivanov, Ivan Dimitrov
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/9/1323