Exosomal transfer of miR-15b-3p enhances tumorigenesis and malignant transformation through the DYNLT1/Caspase-3/Caspase-9 signaling pathway in gastric cancer

Abstract Background Exosomes are essential for tumor growth, metastasis, and are used as novel signaling molecules in targeted therapies. Therefore, exosomal miRNAs can be used in new diagnostic and therapeutic approaches due to their involvement in the development of cancers. However, the detailed...

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Bibliographic Details
Main Authors: Shuchun Wei, Lei Peng, Jiajia Yang, Huaiming Sang, Duochen Jin, Xuan Li, Meihong Chen, Weifeng Zhang, Yini Dang, Guoxin Zhang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-019-1511-6