Neuroprotective Effect of Resveratrol via Activation of Sirt1 Signaling in a Rat Model of Combined Diabetes and Alzheimer’s Disease

Neuroprotective Effect of Resveratrol via Activation of Sirt1 Signaling in a Rat Model of Combined Diabetes and Alzheimer’s Disease

BackgroundAlzheimer’s disease (AD) and diabetes mellitus (DM) often coexist in patients because having one of these conditions increases risk for the other. These two diseases share several pathophysiological mechanisms, such as specific inflammatory signaling pathways, oxidative stress, and cell ap...

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Bibliographic Details
Main Authors: XingRong Ma, ZhiKun Sun, Xiao Han, Shujian Li, Xiaofeng Jiang, Shuai Chen, Jiewen Zhang, Hong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
Subjects:
resveratrol
Alzheimer’s disease
diabetes mellitus
oxidative stress
Aβ1-40
neuroprotective
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01400/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01400/full

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