Nogo receptor inhibition enhances functional recovery following lysolecithin-induced demyelination in mouse optic chiasm.

Nogo receptor inhibition enhances functional recovery following lysolecithin-induced demyelination in mouse optic chiasm.

Inhibitory factors have been implicated in the failure of remyelination in demyelinating diseases. Myelin associated inhibitors act through a common receptor called Nogo receptor (NgR) that plays critical inhibitory roles in CNS plasticity. Here we investigated the effects of abrogating NgR inhibiti...

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Main Authors: Fereshteh Pourabdolhossein, Sabah Mozafari, Ghislaine Morvan-Dubois, Javad Mirnajafi-Zadeh, Alejandra Lopez-Juarez, Jacqueline Pierre-Simons, Barbara A Demeneix, Mohammad Javan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153612?pdf=render

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