Influence of cyclodextrins on the photostability of selected drug molecules in solution and the solid-state
The photostability of selected drug molecules, including furosemide, prochlorperazine, diclofenac, piroxicam, midazolam and nifedipine was studied, the kinetics of photodegradation, identification of the photodegradants investigated and mechanisms of photodegradation proposed. Selected cyclodextrins...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2001-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/S1110662X01000277 |
| Summary: | The photostability of selected drug molecules, including furosemide, prochlorperazine, diclofenac,
piroxicam, midazolam and nifedipine was studied, the kinetics of photodegradation, identification
of the photodegradants investigated and mechanisms of photodegradation proposed. Selected cyclodextrins
altered the photodegradation profiles of diclofenac, piroxicam, midazolam and nifedipine by either accelerating
or retarding the rate of photodegradation and generating novel photodegradants. |
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| ISSN: | 1110-662X |