Catalpol Inhibits Ischemia-Induced Premyelinating Oligodendrocyte Damage through Regulation of Intercellular Calcium Homeostasis via Na+/Ca2+ Exchanger 3

Catalpol Inhibits Ischemia-Induced Premyelinating Oligodendrocyte Damage through Regulation of Intercellular Calcium Homeostasis via Na+/Ca2+ Exchanger 3

The heightened vulnerability of premyelinating oligodendrocytes (PreOLs) in response to hypoxia–ischemia may contribute to perinatal white matter injury and subsequent neurobehavioral dysfunction. Intracellular Ca2+ overload is considered a crucial mechanism predisposing PreOLs to ischemic...

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Bibliographic Details
Main Authors: Qiyan Cai, Teng Ma, Yanping Tian, Chengren Li, Hongli Li
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
catalpol
premyelinating oligodendrocytes
ischemia
calcium homeostasis
Na+/Ca2+ exchanger 3
Online Access:http://www.mdpi.com/1422-0067/19/7/1925

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