Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF-β3

Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF-β3

Abstract Background Due to its low capacity for self-repair, articular cartilage is highly susceptible to damage and deterioration, which leads to the development of degenerative joint diseases such as osteoarthritis (OA). Menstrual blood-derived mesenchymal stem/stromal cells (MenSCs) are much less...

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Bibliographic Details
Main Authors: Ilona Uzieliene, Edvardas Bagdonas, Kazuto Hoshi, Tomoaki Sakamoto, Atsuhiko Hikita, Zivile Tachtamisevaite, Greta Rakauskiene, Giedrius Kvederas, Ali Mobasheri, Eiva Bernotiene
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Stem Cell Research & Therapy
Subjects:
Human mesenchymal stem cells
Menstrual blood
Bone marrow
Chondrogenic differentiation
Activin A
TGF-β3
Online Access:https://doi.org/10.1186/s13287-021-02286-w

Internet

https://doi.org/10.1186/s13287-021-02286-w

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