SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

Summary: The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a current global health emergency, and effective prophylactic vaccines are needed urgently. The spike glycoprotein of SARS-CoV-2 mediates entry into host cells, and thus is the target of neutralizing...

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Bibliographic Details
Main Authors: Marco Mandolesi, Daniel J. Sheward, Leo Hanke, Junjie Ma, Pradeepa Pushparaj, Laura Perez Vidakovics, Changil Kim, Monika Àdori, Klara Lenart, Karin Loré, Xaquin Castro Dopico, Jonathan M. Coquet, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports Medicine
Subjects:
SARS-CoV-2
neutralizing antibodies
protein subunit vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121000689

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http://www.sciencedirect.com/science/article/pii/S2666379121000689

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