Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay.

Analysis of epitopes on dengue virus envelope protein recognized by monoclonal antibodies and polyclonal human sera by a high throughput assay.

BACKGROUND: The envelope (E) protein of dengue virus (DENV) is the major target of neutralizing antibodies and vaccine development. While previous studies on domain III or domain I/II alone have reported several epitopes of monoclonal antibodies (mAbs) against DENV E protein, the possibility of inte...

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Main Authors: Hong-En Lin, Wen-Yang Tsai, I-Ju Liu, Pi-Chun Li, Mei-Ying Liao, Jih-Jin Tsai, Yi-Chieh Wu, Chih-Yun Lai, Chih-Hsuan Lu, Jyh-Hsiung Huang, Gwong-Jen Chang, Han-Chung Wu, Wei-Kung Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3250511?pdf=render

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http://europepmc.org/articles/PMC3250511?pdf=render

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