High spatial resolution nanoslit SERS for single-molecule nucleobase sensing

Direct and real-time identification of nucleobases in DNA strands is still limited by the sensitivity and spatial resolution of the established solid-state nanopore devices. Here, the authors use CMOS compatible, plasmonic nanoslits to locally enable SERS for identifying nucleobases, both individual...

Full description

Bibliographic Details
Main Authors: Chang Chen, Yi Li, Sarp Kerman, Pieter Neutens, Kherim Willems, Sven Cornelissen, Liesbet Lagae, Tim Stakenborg, Pol Van Dorpe
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04118-7