Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate

Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate

A simple route for synthesis of ethyl 2-(3-methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate is developed. The present work involves condensation of 2-(2-nitrobenzamido)propanoic acid with ethyl anthranillate followed by the H2/Pd/C reduction to give the amino ester which upon hea...

Full description

Bibliographic Details
Main Authors:	Naim H. Al-Said, Ayat M. Al-Sghair
Format:	Article
Language:	English
Published:	MDPI AG 2013-12-01
Series:	Molbank
Subjects:	benzo[e][1,4]diazepine ferric chloride cyclization
Online Access:	http://www.mdpi.com/1422-8599/2013/4/M811

Similar Items

Crystal structure of (1Z,4Z)-2,4-dimethyl-3H-benzo[b][1,4]diazepine
by: Carla I. Nieto, et al.
Published: (2017-05-01)

CuI nanoparticles as a remarkable catalyst in the synthesis of benzo[b][1,5]diazepines: an eco-friendly approach
by: Mohammad Ali Ghasemzadeh, et al.
Published: (2014-11-01)

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines
by: E. Angeles, et al.
Published: (2001-07-01)

Synthesis of new seven membered heterocyclic rings: An easy access to indeno-benzo[1,4]diazepines
by: Raza M. Ghalib, et al.
Published: (2020-10-01)

Shortcut Approach to 1,4-Diazepine from 3-Pyridylnitrene Intermedietes under Mild Condition
by: Siti Mariyah Ulfa, et al.
Published: (2014-11-01)

Temperature-Dependent Ordering of the Methyl Group in the Crystal Structure of 5-(2-Chlorophenyl)-7-ethyl-1H-thieno [2,3-E][1,4]diazepin-2(3H)-one
by: Hemmige S. Yathirajan, et al.
Published: (2012-09-01)

Synthesis of new tricyclic 5,6-dihydro-4H-benzo[b][1,2,4]triazolo[1,5-d][1,4]diazepine derivatives by [3+ + 2]-cycloaddition/rearrangement reactions
by: Lin-bo Luan, et al.
Published: (2018-07-01)

A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species
by: Shi-Hai Xu, et al.
Published: (2010-02-01)

Synthesis of some novel 7-(1H-benzimidazol-2-ylazo)-1,3-dimethyl-6,8-disubstituted-1,5-dihydro pyrimido[4,5-b] [1,4] diazepine-2,4-diones as potential antianxiety agents
by: Sharma Kanti, et al.
Published: (2013-01-01)

The Novel [4,5-e][1,3]Diazepine-4,8-dione and Acyclic Carbamoyl Imino-Ureido Derivatives of Imidazole: Synthesis, Anti-Viral and Anti-Tumor Activity Evaluations
by: Karlo Wittine, et al.
Published: (2013-10-01)

1-Benzyl-3-hydroxy-4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
by: Mohammed Rida, et al.
Published: (2016-11-01)

(4Z)-4-(2-Oxopropylidene)-1,3-bis(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
by: Jihad Sebhaoui, et al.
Published: (2017-04-01)

Synthesis of substituted (oxazepine, Diazepine, tetrazde) via Schiff Bases for 2- Aminobenzo Thaizole Derivatives
by: Baghdad Science Journal
Published: (2013-09-01)

Synthesis of Substituted 1,4-Diazepines and 1,5-Benzodiazepines Using an Efficient Heteropolyacid-Catalyzed Procedure
by: Sihame Benadji, et al.
Published: (2010-12-01)

Synthesis of 3-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones and 1-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones
by: Pathki Uma, et al.
Published: (2018-01-01)

Synthesis of novel Indolyl benzo[b][1,4]diazepins as potent antimicrobial and antioxidant agents
by: Jaiprakash S. Biradar, et al.
Published: (2016-11-01)

Synthesis, Bacteriostatic and Anticancer Activity of Novel Phenanthridines Structurally Similar to Benzo[c]phenanthridine Alkaloids
by: Pavel Lasák, et al.
Published: (2018-08-01)

Green synthesis and anxiolytic activity of some new dibenz-[1,4] diazepine-1-one analogues
by: Jaiprakash N. Sangshetti, et al.
Published: (2017-02-01)

Novel 4-Aroyl-3-alkoxy-2(5H)-furanones as Precursors for the Preparation of Furo[3,4-b][1,4]-diazepine Ring System
by: Adel Amer, et al.
Published: (2003-10-01)

Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies
by: Dharmender Rathee, et al.
Published: (2018-04-01)

1-Benzyl-2-(thien-2-yl)-4,5-dihydro-1<i>H</i>-imidazole
by: Alexandra S. Golubenkova, et al.
Published: (2020-05-01)

4-Amino-5-(4-bromo benzo yl)-3-(benzo[d]thia zol-2-yl)-2-[(2′,3′,4′,6′-tetra-O-acetyl-β-d-galacto pyran osyl)sulfanyl] thio phene
by: Azzam, R.A, et al.
Published: (2022)

Crystal structure of (2-methyl-4-phenyl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-3-yl)(phenyl)methanone
by: T. Sankar, et al.
Published: (2015-05-01)

Synthesis of ([1,2,4]triazolo[4,3-a]pyridin-3-ylmethyl)phosphonates and their benzo derivatives via 5-exo-dig cyclization
by: Aleksandr S. Krylov, et al.
Published: (2019-07-01)

Synthesis of 2-Phenylazonaphtho[1,8-ef][1,4]diazepines and 9-(3-Arylhydrazono)pyrrolo[1,2-a]perimidines as Antitumor Agents
by: Thoraya A. Farghaly, et al.
Published: (2014-01-01)

Évaluation du 4,5-dihydrodiol-benzo[a]pyrène et du 7,8-dihydrodiol-benzo[a]pyrène en tant que biomarqueurs spécifiques alternatifs d’exposition au benzo[a]pyrène
by: Odenigbo, Chukwudum
Published: (2019)

Ethyl 1-(4-chlorophenyl)-5,6-dimethyl-7,8a-diphenyl-4,5,6,8a-tetrahydro-1H-[1,2,4] triazolo[4,3-c][1,3]diazine-3-carboxylate
by: A. Boudina, et al.
Published: (2006-03-01)

4-[(3-Phenyl-4,5-dihydroisoxazol-5-yl)methyl]-2H-benzo[b][1,4]thiazin-3(4H)-one
by: Nada Kheira Sebbar, et al.
Published: (2016-06-01)

Palladium-catalyzed synthesis and nucleotide pyrophosphatase inhibition of benzo[4,5]furo[3,2-b]indoles
by: Hoang Huy Do, et al.
Published: (2019-11-01)

Ring-opening benzannulations of cyclopropenes, alkylidene cyclopropanes, and 2,3-dihydrofuran acetals: A complementary approach to benzo-fused (hetero)aromatics
by: Aponte-Guzman, Joel
Published: (2016)

2-(3,4-Dimethoxyphenyl)-<i>N</i>-(4-methoxyphenyl)-1-propyl-1<i>H</i>-benzo[<i>d</i>]imidazole-5-carboxamide
by: Prakash Bhaskar, et al.
Published: (2019-09-01)

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors
by: Abdel Gawad, N.M, et al.
Published: (2022)

Synthesis of 4-OXO-4H-Chromene Derivative with Fused Benzodiazepine Ring
by: Zemanová Ivana, et al.
Published: (2016-06-01)

Crystal structure of (±)-3-[(benzo[d][1,3]dioxol-5-yl)methyl]-2-(3,4,5-trimethoxyphenyl)-1,3-thiazolidin-4-one
by: Rodolfo Moreno-Fuquen, et al.
Published: (2014-12-01)

2,4-Diphenyl-4,5-dihydro-3H-pyrido[2,3-b][1,4]diazepine
by: Shyamaprosad Goswami, et al.
Published: (2009-05-01)

Synthesis of 3,4-Dihydroquinoxalin-2-Amine, Diazepine-Tetrazole and Benzodiazepine-2-Carboxamide Derivatives with the Aid of H6P2W18O62/Pyridino-Fe3O4
by: Akbar Hassanpour, et al.
Published: (2016-12-01)

Benzo[5]radialenos como precursores de fluorenos e benzo[b]fluorenos
by: Andreas Albert Von Richthofen
Published: (2015)

Benzo[5]radialenos como precursores de fluorenos e benzo[b]fluorenos
by: Von Richthofen, Andreas Albert
Published: (2015)

4<i>H</i>-Benzo[<i>d</i>][1,3]oxazin-4-ones and Dihydro Analogs from Substituted Anthranilic Acids and Orthoesters
by: Joel K. Annor-Gyamfi, et al.
Published: (2019-10-01)

7,9-Didodecyl-6-methyl-3H,7H,8H,9H,9aH-[1,2,4]triazolo[4,3-b][1,2,4]triazepin-8-one
by: Youness El Bakri, et al.
Published: (2016-10-01)