Establishment the renal function detection reference interval of healthy pregnant women in Xi’an district

• Main Authors: Man Zhao, Ya Zhao, Ning Li
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2018-08-01
• Series: Journal of Hainan Medical University
• Subjects: Healthy pregnant women; Urea nitrogen; Creatinine; Uric acid; Reference range
• Online Access: http://www.hnykdxxb.com/PDF/201816/17.pdf
• ISSN: 1007-1237; 1007-1237

Objective: To explore whether the serum test reference range of kidney function is suitable for healthy pregnant women in Xi'an and establish normal reference range for healthy pregnant women. Methods: A total of 1 376 healthy pregnant women serum urea nitrogen (BUN), creatinine (CREA), uric acid (UA) is tested by AU5800 automatic biochemical analyzer, compared with healthy non pregnant women, statistical analysis results. At the same time, estimate whether the data shows a normal distribution, and evaluate the reference range of healthy pregnant women according to Mean ± 1.96s. Results: BUN and CERA data are normally distributed, and UA data is in a positive skew distribution. There were statistically significant differences in serum BUN, CERA and UA levels between healthy pregnant women and healthy non-pregnant women. There were statistically significant differences in serum BUN, CERA and UA levels of healthy pregnant women and healthy non-pregnant women in the same age group. The difference was not statistically significant in serum BUN, CERA and UA levels in different age groups of healthy pregnant women. The serum BUN of the healthy pregnant women reference range was lower than the healthy non-pregnant women, and the serum UA reference range of the healthy pregnant women was wider than the healthy non pregnant women. Conclusion: Assessment the renal function status of pregnant women is not reasonable by non-pregnant woman's reference range of BUN, Cr and UA. It is imminent that targeted to establish local regional pregnant women BUN, Cr and UA normal reference range to accurately assess the renal function.