Human and murine macrophages exhibit differential metabolic responses to lipopolysaccharide - A divergent role for glycolysis

Macrophages adopt different phenotypes in response to microenvironmental changes, which can be principally classified into inflammatory and anti-inflammatory states. Inflammatory activation of macrophages has been linked with metabolic reprogramming from oxidative phosphorylation to aerobic glycolys...

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Bibliographic Details
Main Authors: Vijith Vijayan, Pooja Pradhan, Laura Braud, Heiko R. Fuchs, Faikah Gueler, Roberto Motterlini, Roberta Foresti, Stephan Immenschuh
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719300242