Regulation of StAR by the N-terminal domain and co-induction of SIK1 and TIS11b/Znf36l1 in single cells.

Regulation of StAR by the N-terminal domain and co-induction of SIK1 and TIS11b/Znf36l1 in single cells.

The cholesterol transfer function of StAR is uniquely integrated into adrenal cells, with mRNA translation and PKA phosphorylation occurring at the mitochondrial outer membrane (OMM). The StAR C-terminal cholesterol binding domain (CBD) initiates mitochondrial inter-membrane contacts to rapidly dire...

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Bibliographic Details
Main Authors: Jinwoo Lee, Tiegang Tong, Yeehoon Foong, Ibrahim Musaitif, Takeshi Yamazaki, Colin Jefcoate
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Endocrinology
Subjects:
PCR
StAR
fluorescence in situ hybridization
SIK1
Tis11b
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00107/full

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