IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

Glucocorticoids are currently the only drug treatment recognized to benefit Duchenne muscular dystrophy (DMD) patients. The nature of the mechanisms underlying the beneficial effects remains incompletely understood but may involve an increase in the expression of utrophin. Here, we show that treatme...

Full description

Bibliographic Details
Main Authors: Pedro Miura, Meghan Andrews, Martin Holcik, Bernard J Jasmin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2396518?pdf=render

Internet

http://europepmc.org/articles/PMC2396518?pdf=render

Similar Items