Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment
Tumor-homing peptides with tissue-penetrating properties increase the efficacy of targeted cancer therapy by delivering an anticancer agent to the tumor interior. LyP-1 (CGNKRTRGC) and iRGD (CRGDKGPDC) are founding members of this class of peptides. The presence of the cysteines forming the cyclizin...
Main Authors: | Venkata Ramana Kotamraju, Shweta Sharma, Poornima Kolhar, Lilach Agemy, James Pavlovich, Erkki Ruoslahti |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-01-01
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Series: | Breast Cancer: Basic and Clinical Research |
Online Access: | https://doi.org/10.4137/BCBCR.S29426 |
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