Alterations of Both Dendrite Morphology and Weaker Electrical Responsiveness in the Cortex of Hip Area Occur Before Rearrangement of the Motor Map in Neonatal White Matter Injury Model

Alterations of Both Dendrite Morphology and Weaker Electrical Responsiveness in the Cortex of Hip Area Occur Before Rearrangement of the Motor Map in Neonatal White Matter Injury Model

Hypoxia-ischemia (H-I) in rats at postnatal day 3 causes disorganization of oligodendrocyte development in layers II/III of the sensorimotor cortex without apparent neuronal loss, and shows mild hindlimb dysfunction with imbalanced motor coordination. However, the mechanisms by which mild motor dysf...

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Bibliographic Details
Main Authors: Yoshitomo Ueda, Yoshio Bando, Sachiyo Misumi, Shino Ogawa, Akimasa Ishida, Cha-Gyun Jung, Takeshi Shimizu, Hideki Hida
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neurology
Subjects:
hypoxia-ischemia in premature infants
white matter injury
intracortical microstimulation (ICMS)
golgi staining
cortical layer I-III
hip area
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00443/full

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