Ethanol treatment of nanoPGA/PCL composite scaffolds enhances human chondrocyte development in the cellular microenvironment of tissue-engineered auricle constructs.

Ethanol treatment of nanoPGA/PCL composite scaffolds enhances human chondrocyte development in the cellular microenvironment of tissue-engineered auricle constructs.

A major obstacle for tissue engineering ear-shaped cartilage is poorly developed tissue comprising cell-scaffold constructs. To address this issue, bioresorbable scaffolds of poly-ε-caprolactone (PCL) and polyglycolic acid nanofibers (nanoPGA) were evaluated using an ethanol treatment step before au...

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Bibliographic Details
Main Authors: Narihiko Hirano, Hirohisa Kusuhara, Yu Sueyoshi, Takeshi Teramura, Ananth Murthy, Shinichi Asamura, Noritaka Isogai, Robin DiFeo Jacquet, William J Landis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0253149

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https://doi.org/10.1371/journal.pone.0253149

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