Ion-Selective Carbon Nanotube Field-Effect Transistors for Monitoring Drug Effects on Nicotinic Acetylcholine Receptor Activation in Live Cells

Ion-Selective Carbon Nanotube Field-Effect Transistors for Monitoring Drug Effects on Nicotinic Acetylcholine Receptor Activation in Live Cells

We developed ion-selective field-effect transistor (FET) sensors with floating electrodes for the monitoring of the potassium ion release by the stimulation of nicotinic acetylcholine receptors (nAChRs) on PC12 cells. Here, ion-selective valinomycin-polyvinyl chloride (PVC) membranes were coated on...

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Bibliographic Details
Main Authors: Youngtak Cho, Viet Anh Pham Ba, Jin-Young Jeong, Yoonji Choi, Seunghun Hong
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Sensors
Subjects:
carbon nanotube field-effect transistor
ion-selective membrane
valinomycin
nicotinic acetylcholine receptor
ion channel
Online Access:https://www.mdpi.com/1424-8220/20/13/3680

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