S100A8/A9 mRNA induction in an ex vivo model of endotoxin tolerance: roles of IL-10 and IFNγ.

Septic syndromes are the leading cause of death in intensive care units. They are characterized by the development of immune dysfunctions such as endotoxin tolerance (ET), whose intensity and duration are associated with increased risk of nosocomial infections and mortality. Alarmins S100A8 and S100...

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Bibliographic Details
Main Authors: Mathieu Fontaine, Séverine Planel, Estelle Peronnet, Fanny Turrel-Davin, Vincent Piriou, Alexandre Pachot, Guillaume Monneret, Alain Lepape, Fabienne Venet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4067416?pdf=render