Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients

Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients

Abstract Xanthine oxidase (XO) competes with thiopurine S‐methyltransferase (TPMT) and hypoxanthine guanine phosphoribosyltransferase (HPRT) to metabolize azathioprine (AZA)/6‐mercaptopurine (6‐MP) in vivo. A retrospective investigation was performed to detect the activity of XO in thiopurine curati...

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Bibliographic Details
Main Authors: Liang Ding, Fang‐bin Zhang, Hui Liu, Xiang Gao, Hui‐chang Bi, Ling Huang, Xue‐ding Wang, Bai‐li Chen, Yu Zhang, Chuanzhu Lv, Pin‐jin Hu, Min Huang
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Pharmacology Research & Perspectives
Subjects:
6‐mercaptopurine
AZA thioprine
inflammatory bowel disease
xanthine oxidase
Online Access:https://doi.org/10.1002/prp2.764

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