Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy

Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy

Animal studies have shown diabetes-induced lysyl oxidase (LOX) upregulation promotes blood-retinal-barrier breakdown and retinal vascular cell loss associated with diabetic retinopathy (DR). However, it is unclear whether changes in LOX expression contribute to the development and progression of DR....

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Bibliographic Details
Main Authors: Manju L. Subramanian, Thor D. Stein, Nicole Siegel, Steven Ness, Marissa G. Fiorello, Dongjoon Kim, Sayon Roy
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
lysyl oxidase
hyperglycemia
diabetic retinopathy
retinal lesions
Online Access:https://www.mdpi.com/2073-4409/8/10/1122

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https://www.mdpi.com/2073-4409/8/10/1122

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