Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain

Noxious stimuli are detected by peripheral nociceptors and then transmitted to higher CNS centers, where they are perceived as an unpleasant sensation. The mechanisms that govern the emotional component associated with pain are still incompletely understood. Here, we used optogenetic approaches both...

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Bibliographic Details
Main Authors: Zizhen Zhang, Vinicius M. Gadotti, Lina Chen, Ivana A. Souza, Patrick L. Stemkowski, Gerald W. Zamponi
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715007275