EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT

EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT

Abstract.  We  studied  effects  of  Stimforte,  an  immunomodulatory  drug  of  animal  origin,  upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and s...

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Main Authors: D. G. Maldov, A. V. Ilychev, E. A. Lebedinskaya, E. V. Fadeeva, O. V. Lebedinskaya, N. K. Akhmatova, V. A. Chetvertnykh, A. P. Godovalov, S. V. Melekhin, M. V. Kiselevsky
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
immune suppression
cyclophosphan
stimforte
immunomodulatory drugs
Online Access:https://www.mimmun.ru/mimmun/article/view/500
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spelling doaj-7ce5e89d1161473babc97583d78087c12021-07-29T09:02:26ZrusSPb RAACIMedicinskaâ Immunologiâ1563-06252313-741X2014-07-01132-313313810.15789/1563-0625-2011-2-3-133-138497EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENTD. G. Maldov0A. V. Ilychev1E. A. Lebedinskaya2E. V. Fadeeva3O. V. Lebedinskaya4N. K. AkhmatovaV. A. Chetvertnykh5A. P. Godovalov6S. V. Melekhin7M. V. Kiselevsky8ЗАО СКАЙ-ЛТД, МоскваЗАО СКАЙ-ЛТД, МоскваГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГОУ ВПО «Пермская государственная медицинская академия им. ак. Е.А. Вагнера» Росздрава, г. ПермьГУ «Российский онкологический научный центр им. Н.Н. Блохина РАМН», МоскваAbstract.  We  studied  effects  of  Stimforte,  an  immunomodulatory  drug  of  animal  origin,  upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and subpopulational composition of splenic MLs, the structure of central and peripheral lymphopoietic tissues, as well as effector cell functions of innate immunity affected by the cytostatic drug. (Med. Immunol., 2011, vol. 13, N 2-3, pp 133-138)https://www.mimmun.ru/mimmun/article/view/500immune suppressioncyclophosphanstimforteimmunomodulatory drugs
collection DOAJ
language Russian
format Article
sources DOAJ
author D. G. Maldov
A. V. Ilychev
E. A. Lebedinskaya
E. V. Fadeeva
O. V. Lebedinskaya
N. K. Akhmatova
V. A. Chetvertnykh
A. P. Godovalov
S. V. Melekhin
M. V. Kiselevsky
spellingShingle D. G. Maldov
A. V. Ilychev
E. A. Lebedinskaya
E. V. Fadeeva
O. V. Lebedinskaya
N. K. Akhmatova
V. A. Chetvertnykh
A. P. Godovalov
S. V. Melekhin
M. V. Kiselevsky
EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
Medicinskaâ Immunologiâ
immune suppression
cyclophosphan
stimforte
immunomodulatory drugs
author_facet D. G. Maldov
A. V. Ilychev
E. A. Lebedinskaya
E. V. Fadeeva
O. V. Lebedinskaya
N. K. Akhmatova
V. A. Chetvertnykh
A. P. Godovalov
S. V. Melekhin
M. V. Kiselevsky
author_sort D. G. Maldov
title EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
title_short EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
title_full EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
title_fullStr EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
title_full_unstemmed EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT
title_sort effect of stimforte upon murine mononuclear leukocytes and lymphoid organs during cyclophosphan treatment
publisher SPb RAACI
series Medicinskaâ Immunologiâ
issn 1563-0625
2313-741X
publishDate 2014-07-01
description Abstract.  We  studied  effects  of  Stimforte,  an  immunomodulatory  drug  of  animal  origin,  upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression. It was demonstrated that Stimforte is able to correct the quantitative and subpopulational composition of splenic MLs, the structure of central and peripheral lymphopoietic tissues, as well as effector cell functions of innate immunity affected by the cytostatic drug. (Med. Immunol., 2011, vol. 13, N 2-3, pp 133-138)
topic immune suppression
cyclophosphan
stimforte
immunomodulatory drugs
url https://www.mimmun.ru/mimmun/article/view/500
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