Driving regeneration, instead of healing, in adult mammals: the decisive role of resident macrophages through efferocytosis

Driving regeneration, instead of healing, in adult mammals: the decisive role of resident macrophages through efferocytosis

Abstract Tissue repair after lesion usually leads to scar healing and thus loss of function in adult mammals. In contrast, other adult vertebrates such as amphibians have the ability to regenerate and restore tissue homeostasis after lesion. Understanding the control of the repair outcome is thus a...

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Bibliographic Details
Main Authors: Lise Rabiller, Virginie Robert, Adèle Arlat, Elodie Labit, Marielle Ousset, Marie Salon, Agnès Coste, Léa Da Costa-Fernandes, Paul Monsarrat, Bruno Ségui, Mireille André, Christophe Guissard, Marie-Laure Renoud, Marine Silva, Gilles Mithieux, Isabelle Raymond-Letron, Luc Pénicaud, Anne Lorsignol, Louis Casteilla, Cécile Dromard Berthézène, Béatrice Cousin
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00151-1

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