Insulin-Producing Cells from Adult Human Bone Marrow Mesenchymal Stem Cells Control Streptozotocin-Induced Diabetes in Nude Mice

Insulin-Producing Cells from Adult Human Bone Marrow Mesenchymal Stem Cells Control Streptozotocin-Induced Diabetes in Nude Mice

Harvesting, expansion, and directed differentiation of human bone marrow-derived mesenchymal stem cells (BM-MSCs) could provide an autologous source of surrogate β-cells that would alleviate the limitations of availability and/or allogenic rejection following pancreatic or islet transplantation. Bon...

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Bibliographic Details
Main Authors: Mahmoud M. Gabr, Mahmoud M. Zakaria, Ayman F. Refaie, Amani M. Ismail, Mona A. Abou-El-Mahasen, Sylvia A. Ashamallah, Sherry M. Khater, Sawsan M. El-Halawani, Rana Y. Ibrahim, Gan Shu Uin, Malgorzata Kloc, Roy Y. Calne, Mohamed A. Ghoneim M.D., M.D. (Hon.), FACS (Hon.)
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X647162

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