Effects of cellular cholesterol loading on macrophage foam cell lysosome acidifications⃞

Macrophages incubated with mildly oxidized low density lipoprotein (OxLDL), aggregated low density lipoprotein (AggLDL), or cholesteryl ester-rich lipid dispersions (DISPs) accumulate cholesterol in lysosomes followed by an inhibition of lysosomal cholesteryl ester (CE) hydrolysis. The variety of ch...

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Bibliographic Details
Main Authors: Brian E. Cox, Evelyn E. Griffin, Jody C. Ullery, Jerome W. Gray
Format: Article
Language:English
Published: Elsevier 2007-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435473