Effects of cellular cholesterol loading on macrophage foam cell lysosome acidifications⃞
Macrophages incubated with mildly oxidized low density lipoprotein (OxLDL), aggregated low density lipoprotein (AggLDL), or cholesteryl ester-rich lipid dispersions (DISPs) accumulate cholesterol in lysosomes followed by an inhibition of lysosomal cholesteryl ester (CE) hydrolysis. The variety of ch...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520435473 |