Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor

Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor

Recent developments in cancer treatment are demonstrating the increasing and powerful potential of immunotherapeutic strategies. In this regard, the adoptive transfer of tumor-specific T-lymphocytes approaches can lead to tumor regression in cancer patients. More recently, the use of T-cells genetic...

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Bibliographic Details
Main Authors: Vasyl Eisenberg, Katerina Shamalov, Shimrit Meir, Shiran Hoogi, Rhitajit Sarkar, Shirel Pinker, Gal Markel, Angel Porgador, Cyrille J. Cohen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
NCR2
T-cells engineering
chimeric receptors
adoptive T-cell transfer
T-cell immunotherapy
natural killer cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01212/full

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