ACE inhibitor quinapril in the treatment of chronic cardiac failure

• Main Author: A N Gadzhiev
• Format: Article
• Language: Russian
• Published: "Consilium Medicum" Publishing house 2003-01-01
• Series: Терапевтический архив
• Subjects: chronic heart failure; inhibitors of angiotensin convening enzyme; left ventricle remodeling; heart rhythm variability; late potentials
• Online Access: https://ter-arkhiv.ru/0040-3660/article/view/29292

Aim. To assess effectiveness of A CE inhibitor quinapril in patients with moderate cardiac failure of ischemic etiology. Material and methods. 20 patients received quinapril in a daily dose 20 mgfor 6 months. Clinical condition, exercise tolerance, functional and geometric parameters of the left ventricle, Hotter monitoring, heart rhythm variability, late potentials were studied before and after the treatment. Results. The treatment relieved symptoms significantly, exercise tolerance increased, positive changes occurred in systotic, diastolic functions and left ventricular geometry. Ischemic episodes, supraventricular extrasystoles reduced in number and duration. Conclusion. Quinapril is an effective drug for treatment of moderate ischemic heart failure.