Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART.

Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART.

<h4>Background and aims</h4>Although combined antiretroviral treatment (cART) has improved overall survival of HIV infected patients, liver fibrosis and liver related-mortality still constitute major challenges in HIV positive patients. Collagen accumulates in the liver during fibrogenes...

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Bibliographic Details
Main Authors: Leona Dold, Mette J Nielsen, Michael Praktiknjo, Carolynne Schwarze-Zander, Christoph Boesecke, Robert Schierwagen, Raphael Mohr, Jan-Christian Wasmuth, Christian Jansen, Jenny Bischoff, Jürgen Kurt Rockstroh, Morten A Karsdal, Ulrich Spengler, Jonel Trebicka, Diana J Leeming
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219526

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