Cigarette smoke extract enhances neutrophil elastase-induced IL-8 production via proteinase-activated receptor-2 upregulation in human bronchial epithelial cells

Cigarette smoke extract enhances neutrophil elastase-induced IL-8 production via proteinase-activated receptor-2 upregulation in human bronchial epithelial cells

Lung disease: How cigarette smoking enhances lung inflammation A study of the effect of cigarette smoke extract (CSE) on lung lining cells clarifies the interaction between CSE and an enzyme implicated in causing chronic obstructive pulmonary disease (COPD). The enzyme elastase is released by neutro...

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Bibliographic Details
Main Authors:	Kyoung-Hee Lee, Jinwoo Lee, Jiyeong Jeong, Jisu Woo, Chang-Hoon Lee, Chul-Gyu Yoo
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-07-01
Series:	Experimental and Molecular Medicine
Online Access:	https://doi.org/10.1038/s12276-018-0114-1

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