Screening of Bacterial Quorum Sensing Inhibitors in a <i>Vibrio fischeri</i> LuxR-Based Synthetic Fluorescent <i>E. coli</i> Biosensor

Screening of Bacterial Quorum Sensing Inhibitors in a <i>Vibrio fischeri</i> LuxR-Based Synthetic Fluorescent <i>E. coli</i> Biosensor

A library of 23 pure compounds of varying structural and chemical characteristics was screened for their quorum sensing (QS) inhibition activity using a synthetic fluorescent <i>Escherichia coli</i> biosensor that incorporates a modified version of lux regulon of <i>Vibrio fischeri...

Full description

Bibliographic Details
Main Authors: Xiaofei Qin, Celina Vila-Sanjurjo, Ratna Singh, Bodo Philipp, Francisco M. Goycoolea
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
compounds screening
quorum sensing inhibition
antibacterial
molecular docking
Online Access:https://www.mdpi.com/1424-8247/13/9/263

Similar Items

Similar Items