Characterization of Single Nucleotide Variants of OPN3 Gene in Melanocytic Nevi and Melanoma

In this study, we examined single nucleotide variants (SNVs) of the OPN3 gene in malignant melanoma and melanocytic nevi. A total of 20 variants of SNVs were detected. Of these variants, five nonsynonymous mutations of OPN3 were identified, including c.T152C, c.T401C, c.G547A, c.G768A, and c.G992A....

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Bibliographic Details
Main Authors: Wei Zhang, Jianglong Feng, Wen Zeng, Zhixu Zhou, Yu Wang, Hongguang Lu
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:JID Innovations
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026721000060