Cardiac 123I-MIBG Scintigraphy in Neurodegenerative Parkinson Syndromes: Performance and Pitfalls in Clinical Practice

Cardiac 123I-MIBG Scintigraphy in Neurodegenerative Parkinson Syndromes: Performance and Pitfalls in Clinical Practice

Purpose: Cardiac [123I]metaiodobenzylguanidine scintigraphy (123I-MIBG), reflecting postganglionic cardiac autonomic denervation, is proposed for early detection of Parkinson's disease (PD; reduced tracer uptake) and separation from Multiple System Atrophy (MSA; preserved tracer uptake). Howeve...

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Bibliographic Details
Main Authors: Cornelia Skowronek, Leonora Zange, Axel Lipp
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neurology
Subjects:
Parkinson‘s disease
Lewy body disorders
multiple system atrophy
MIBG scintigraphy
autonomic function
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00152/full

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