Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.

Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.

BACKGROUND: Like human immunodeficiency virus (HIV), ovine lentivirus (OvLV) is macrophage-tropic and causes lifelong infection. OvLV infects one quarter of U.S. sheep and induces pneumonia and body condition wasting. There is no vaccine to prevent OvLV infection and no cost-effective treatment for...

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Bibliographic Details
Main Authors: Stephen N White, Michelle R Mousel, Lynn M Herrmann-Hoesing, James O Reynolds, Kreg A Leymaster, Holly L Neibergs, Gregory S Lewis, Donald P Knowles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3474742?pdf=render

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