Impact of drug solvents on C. elegans pharyngeal pumping

Caenorhabditis elegans provides a multi-cellular model organism for toxicology and drug discovery. These studies usually require solvents such as dimethyl sulfoxide (DMSO), ethanol or acetone as a vehicle. This raises the need to carefully consider whether the chemical vehicles used in these screens...

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Bibliographic Details
Main Authors: Fernando Calahorro, Lindy Holden-Dye, Vincent O’Connor
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221475002100113X