Transcriptome-Wide Analysis Reveals the Role of PPARγ Controlling the Lipid Metabolism in Goat Mammary Epithelial Cells

Transcriptome-Wide Analysis Reveals the Role of PPARγ Controlling the Lipid Metabolism in Goat Mammary Epithelial Cells

To explore the large-scale effect of peroxisome proliferator-activated receptor γ (PPARG) in goat mammary epithelial cells (GMEC), an oligonucleotide microarray platform was used for transcriptome profiling in cells overexpressing PPARG and incubated with or without rosiglitazone (ROSI, a PPARγ agon...

Full description

Bibliographic Details
Main Authors:	Hengbo Shi, Wangsheng Zhao, Changhui Zhang, Khuram Shahzad, Jun Luo, Juan J. Loor
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/2016/9195680

Similar Items

Nutrigenomic Effect of Saturated and Unsaturated Long Chain Fatty Acids on Lipid-Related Genes in Goat Mammary Epithelial Cells: What Is the Role of PPARγ?
by: Einar Vargas-Bello-Pérez, et al.
Published: (2019-06-01)

PPARγ Regulates Genes Involved in Triacylglycerol Synthesis and Secretion in Mammary Gland Epithelial Cells of Dairy Goats
by: Hengbo Shi, et al.
Published: (2013-01-01)

Comprehensive Transcriptome Profiling of Dairy Goat Mammary Gland Identifies Genes and Networks Crucial for Lactation and Fatty Acid Metabolism
by: Cong Li, et al.
Published: (2020-09-01)

MiR130b-Regulation of PPARγ Coactivator- 1α Suppresses Fat Metabolism in Goat Mammary Epithelial Cells.
by: Zhi Chen, et al.
Published: (2015-01-01)

Bioinformatics and Gene Network Analyses of the Swine Mammary Gland Transcriptome during Late Gestation
by: Wangsheng Zhao, et al.
Published: (2013-01-01)

Bioinformatics and Gene Network Analyses of the Swine Mammary Gland Transcriptome during Late Gestation
by: Wangsheng Zhao, et al.
Published: (2013-07-01)

Fatty Acid Elongase 7 (ELOVL7) Plays a Role in the Synthesis of Long-Chain Unsaturated Fatty Acids in Goat Mammary Epithelial Cells
by: Hengbo Shi, et al.
Published: (2019-06-01)

Lipid metabolome-wide effects of the PPARγ agonist rosiglitazones⃞
by: Steven M. Watkins, et al.
Published: (2002-11-01)

mTORC2 Regulates Lipogenic Gene Expression through PPARγ to Control Lipid Synthesis in Bovine Mammary Epithelial Cells
by: Zhixin Guo, et al.
Published: (2019-01-01)

THE MAMMARY EPITHELIAL CELL-SPECIFIC ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ IN DMBA-MEDIATED BREAST TUMOURIGENESIS
by: Roche, JENNIFER
Published: (2008)

Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells
by: Omar Bulgari, et al.
Published: (2017-04-01)

Lipoprotein Lipase, Tissue Expression and Effects on Genes Related to Fatty Acid Synthesis in Goat Mammary Epithelial Cells
by: Wang-Sheng Zhao, et al.
Published: (2014-12-01)

miR-25 modulates triacylglycerol and lipid accumulation in goat mammary epithelial cells by repressing PGC-1beta
by: Liuan Ma, et al.
Published: (2018-06-01)

Gene network and pathway analysis of bovine mammary tissue challenged with <it>Streptococcus uberis </it>reveals induction of cell proliferation and inhibition of PPARγ signaling as potential mechanism for the negative relationships between immune response and lipid metabolism
by: Rodriguez-Zas Sandra L, et al.
Published: (2009-11-01)

Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix
by: Stephen S. Wanyonyi, et al.
Published: (2017-12-01)

Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.
by: Nadine Segond, et al.
Published: (2013-01-01)

<i>Pparγ1 </i>Facilitates ErbB2-Mammary Adenocarcinoma in Mice
by: Xuanmao Jiao, et al.
Published: (2021-04-01)

The Effects of Matrix Metalloproteinase-9 on Dairy Goat Mastitis and Cell Survival of Goat Mammary Epithelial Cells.
by: Hui Li, et al.
Published: (2016-01-01)

Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity
by: Nicholas Pervolarakis, et al.
Published: (2020-10-01)

Epidermal Growth Factor Stimulates Fatty Acid Synthesis Mainly via PLC-γ1/Akt Signaling Pathway in Dairy Goat Mammary Epithelial Cells
by: Jiangtao Huang, et al.
Published: (2020-05-01)

COX-2 and PPARγ expression are potential markers of recurrence risk in mammary duct carcinoma in-situ
by: Wiley Elizabeth L, et al.
Published: (2008-01-01)

Control of brown adipose tissue glucose and lipid metabolism by PPARγ
by: William T. Festuccia, et al.
Published: (2011-12-01)

PPARadigms and PPARadoxes: expanding roles for PPARγ in the control of lipid metabolism
by: Robert Walczak, et al.
Published: (2002-02-01)

Bzw2 Promotes Proliferation and Lactation of Mammary Epithelial Cell in Dairy Goat
by: Rui-qiu SUN, et al.
Published: (2012-11-01)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
by: Ajit A. Kulkarni, et al.
Published: (2012-01-01)

cAMP Response Element Binding Protein 1 (CREB1) Promotes Monounsaturated Fatty Acid Synthesis and Triacylglycerol Accumulation in Goat Mammary Epithelial Cells
by: Dawei Yao, et al.
Published: (2020-10-01)

Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue
by: Anil K. G. Kadegowda, et al.
Published: (2013-01-01)

Determination of Oxidized Lipids in Commonly Consumed Foods and Their Binding Affinity for PPARγ
by: Skinner, Joanna P
Published: (2012)

Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
by: Dagher Hayat, et al.
Published: (2010-02-01)

Curcumin Suppresses Intestinal Fibrosis by Inhibition of PPARγ-Mediated Epithelial-Mesenchymal Transition
by: Su Xu, et al.
Published: (2017-01-01)

Transcriptomics and flow cytometry reveals the cytotoxicity of aflatoxin B1 and aflatoxin M1 in bovine mammary epithelial cells
by: Kuntan Wu, et al.
Published: (2021-02-01)

Comparative transcriptome analysis of mammary epithelial cells at different stages of lactation reveals wide differences in gene expression and pathways regulating milk synthesis between Jersey and Kashmiri cattle.
by: Shakil Ahmad Bhat, et al.
Published: (2019-01-01)

PPARγ, neuroinflammation, and disease
by: Mrak Robert E, et al.
Published: (2004-05-01)

PPAR-γ in the Cardiovascular System
by: Sheng Zhong Duan, et al.
Published: (2008-01-01)

Nutraceuticals as Ligands of PPARγ
by: Meera Penumetcha, et al.
Published: (2012-01-01)

PPARγ and Cognitive Performance
by: Michele d’Angelo, et al.
Published: (2019-10-01)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex.
by: Justin A Lemkul, et al.
Published: (2015-01-01)

Specificity Protein 1 Regulates Gene Expression Related to Fatty Acid Metabolism in Goat Mammary Epithelial Cells
by: Jiangjiang Zhu, et al.
Published: (2015-01-01)

Mammary Transcriptome Profile during Peak and Late Lactation Reveals Differentially Expression Genes Related to Inflammation and Immunity in Chinese Holstein
by: Ziyin Han, et al.
Published: (2020-03-01)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
by: Robert I. Glazer, et al.
Published: (2008-01-01)

Cannot write session to /tmp/vufind_sessions/sess_s2bs9nuohbh7uharlb10d0kc8c