Targeted Sequencing of FKBP5 in Suicide Attempters with Bipolar Disorder.

Targeted Sequencing of FKBP5 in Suicide Attempters with Bipolar Disorder.

FKBP5 is a critical component of the Hypothalamic-Pituitary-Adrenal (HPA) axis, a system which regulates our response to stress. It forms part of a complex of chaperones, which inhibits binding of cortisol and glucocorticoid receptor translocation to the nucleus. Variations in both the HPA axis and...

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Bibliographic Details
Main Authors: Marie E Breen, Sophia C Gaynor, Eric T Monson, Kelly de Klerk, Meredith G Parsons, Terry A Braun, Adam P DeLuca, Peter P Zandi, James B Potash, Virginia L Willour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5193409?pdf=render

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