Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride
Propofol and remifentanil often need to be co-administered via the same intravenous catheter line, which predisposes to potential compatibility issues. Our aim was to determine and compare the emulsion stability of three propofol formulations, two with medium chain triglycerides and one with long ch...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
De Gruyter
2019-08-01
|
Series: | Pharmaceutical Technology in Hospital Pharmacy |
Subjects: | |
Online Access: | https://doi.org/10.1515/pthp-2019-0014 |
id |
doaj-7c5e73e68ef9434d8c047d235d4bca72 |
---|---|
record_format |
Article |
spelling |
doaj-7c5e73e68ef9434d8c047d235d4bca722021-10-02T19:03:45ZengDe GruyterPharmaceutical Technology in Hospital Pharmacy2365-24112365-242X2019-08-0142778710.1515/pthp-2019-0014Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil HydrochlorideNilsson Niklas0Nezvalova-Henriksen Katerina1Tho Ingunn2Department of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, P.O.Box 1068 Blindern, Oslo0371, Norway; Oslo Hospital Pharmacy, Rikshospitalet, NorwayOslo Hospital Pharmacy, Rikshospitalet, Hospital Pharmacy Enterprise, Oslo0372, NorwayDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, P.O.Box 1068 Blindern, Oslo0371, NorwayPropofol and remifentanil often need to be co-administered via the same intravenous catheter line, which predisposes to potential compatibility issues. Our aim was to determine and compare the emulsion stability of three propofol formulations, two with medium chain triglycerides and one with long chain triglycerides, when administered together with remifentanil hydrochloride.https://doi.org/10.1515/pthp-2019-0014compatibilitysafe intravenous administrationanesthesiadroplet growthdestabilisationpfat5 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nilsson Niklas Nezvalova-Henriksen Katerina Tho Ingunn |
spellingShingle |
Nilsson Niklas Nezvalova-Henriksen Katerina Tho Ingunn Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride Pharmaceutical Technology in Hospital Pharmacy compatibility safe intravenous administration anesthesia droplet growth destabilisation pfat5 |
author_facet |
Nilsson Niklas Nezvalova-Henriksen Katerina Tho Ingunn |
author_sort |
Nilsson Niklas |
title |
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride |
title_short |
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride |
title_full |
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride |
title_fullStr |
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride |
title_full_unstemmed |
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride |
title_sort |
emulsion stability of different intravenous propofol formulations in simulated co-administration with remifentanil hydrochloride |
publisher |
De Gruyter |
series |
Pharmaceutical Technology in Hospital Pharmacy |
issn |
2365-2411 2365-242X |
publishDate |
2019-08-01 |
description |
Propofol and remifentanil often need to be co-administered via the same intravenous catheter line, which predisposes to potential compatibility issues. Our aim was to determine and compare the emulsion stability of three propofol formulations, two with medium chain triglycerides and one with long chain triglycerides, when administered together with remifentanil hydrochloride. |
topic |
compatibility safe intravenous administration anesthesia droplet growth destabilisation pfat5 |
url |
https://doi.org/10.1515/pthp-2019-0014 |
work_keys_str_mv |
AT nilssonniklas emulsionstabilityofdifferentintravenouspropofolformulationsinsimulatedcoadministrationwithremifentanilhydrochloride AT nezvalovahenriksenkaterina emulsionstabilityofdifferentintravenouspropofolformulationsinsimulatedcoadministrationwithremifentanilhydrochloride AT thoingunn emulsionstabilityofdifferentintravenouspropofolformulationsinsimulatedcoadministrationwithremifentanilhydrochloride |
_version_ |
1716848286387666944 |