Triterpene Acid (3-O-p-Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc Protein

Triterpene Acid (3-O-p-Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc Protein

Cancer stem cells (CSCs) are drug-resistant and radiation-resistant cancer cells that are responsible for tumor progression and maintenance, cancer recurrence, and metastasis. Targeting breast CSCs with phytochemicals is a new paradigm for cancer prevention and treatment. In this study, activity-gui...

Full description

Bibliographic Details
Main Authors: Hack Sun Choi, Su-Lim Kim, Ji-Hyang Kim, Hong-Yuan Deng, Bong-Sik Yun, Dong-Sun Lee
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer stem cells (CSCs)
3-O-p-coumaroyltormentic acid
mammospheres
c-Myc
Online Access:http://www.mdpi.com/1422-0067/19/9/2528

Internet

http://www.mdpi.com/1422-0067/19/9/2528

Similar Items