MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial–mesenchymal transition of hepatocellular carcinoma

MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial–mesenchymal transition of hepatocellular carcinoma

Abstract Background Tumor-associated macrophages (TAMs) are generally recognized as a promoter of tumor progression. miR-98 has been shown to suppress the proliferation, migration, invasion and epithelial–mesenchymal transition (EMT) of hepatocellular carcinoma (HCC) cells. Here, we aim to investiga...

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Bibliographic Details
Main Authors: Lei Li, Pengfei Sun, Chengsheng Zhang, Zongchao Li, Kai Cui, Wuyuan Zhou
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cancer Cell International
Subjects:
miR-98
Macrophage polarization
Tumor-associated macrophages
Epithelial–mesenchymal transition
Hepatocellular carcinoma
Online Access:http://link.springer.com/article/10.1186/s12935-018-0590-3

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