Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, is a promising recurrence prediction biomarker in colorectal cancer

Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, is a promising recurrence prediction biomarker in colorectal cancer

Abstract The current histopathological risk-stratification criteria in colorectal cancer (CRC) patients following a curative surgery remain inadequate. In this study, we undertook a systematic, genomewide, biomarker discovery approach to identify and validate key EMT-associated genes that may facili...

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Bibliographic Details
Main Authors: Takatoshi Matsuyama, Toshiaki Ishikawa, Naoki Takahashi, Yasuhide Yamada, Masamichi Yasuno, Tatsuyuki Kawano, Hiroyuki Uetake, Ajay Goel
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Molecular Cancer
Subjects:
ITGBL1
Prognostic marker
Epithelial mesenchymal transition
Colorectal cancer
Online Access:http://link.springer.com/article/10.1186/s12943-019-0945-y

Internet

http://link.springer.com/article/10.1186/s12943-019-0945-y

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