An ImmunoSignature test distinguishes Trypanosoma cruzi, hepatitis B, hepatitis C and West Nile virus seropositivity among asymptomatic blood donors.

The complexity of the eukaryotic parasite Trypanosoma (T.) cruzi manifests in its highly dynamic genome, multi-host life cycle, progressive morphologies and immune-evasion mechanisms. Accurate determination of infection or Chagas' disease activity and prognosis continues to challenge researcher...

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Bibliographic Details
Main Authors: Michael Rowe, Jonathan Melnick, Robert Gerwien, Joseph B Legutki, Jessica Pfeilsticker, Theodore M Tarasow, Kathryn F Sykes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5600393?pdf=render