Diabetic Retinopathy: Animal Models, Therapies, and Perspectives

Diabetic Retinopathy: Animal Models, Therapies, and Perspectives

Diabetic retinopathy (DR) is one of the major complications of diabetes. Although great efforts have been made to uncover the mechanisms underlying the pathology of DR, the exact causes of DR remain largely unknown. Because of multifactor involvement in DR etiology, currently no effective therapeuti...

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Main Authors: Xue Cai, James F. McGinnis
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/3789217
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spelling doaj-7c3c7acee1f84d9a81f5c3fefa78b76f2020-11-24T23:25:37ZengHindawi LimitedJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/37892173789217Diabetic Retinopathy: Animal Models, Therapies, and PerspectivesXue Cai0James F. McGinnis1Department of Ophthalmology, Dean McGee Eye Institute, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USADepartment of Ophthalmology, Dean McGee Eye Institute, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USADiabetic retinopathy (DR) is one of the major complications of diabetes. Although great efforts have been made to uncover the mechanisms underlying the pathology of DR, the exact causes of DR remain largely unknown. Because of multifactor involvement in DR etiology, currently no effective therapeutic treatments for DR are available. In this paper, we review the pathology of DR, commonly used animal models, and novel therapeutic approaches. Perspectives and future directions for DR treatment are discussed.http://dx.doi.org/10.1155/2016/3789217
collection DOAJ
language English
format Article
sources DOAJ
author Xue Cai
James F. McGinnis
spellingShingle Xue Cai
James F. McGinnis
Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
Journal of Diabetes Research
author_facet Xue Cai
James F. McGinnis
author_sort Xue Cai
title Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
title_short Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
title_full Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
title_fullStr Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
title_full_unstemmed Diabetic Retinopathy: Animal Models, Therapies, and Perspectives
title_sort diabetic retinopathy: animal models, therapies, and perspectives
publisher Hindawi Limited
series Journal of Diabetes Research
issn 2314-6745
2314-6753
publishDate 2016-01-01
description Diabetic retinopathy (DR) is one of the major complications of diabetes. Although great efforts have been made to uncover the mechanisms underlying the pathology of DR, the exact causes of DR remain largely unknown. Because of multifactor involvement in DR etiology, currently no effective therapeutic treatments for DR are available. In this paper, we review the pathology of DR, commonly used animal models, and novel therapeutic approaches. Perspectives and future directions for DR treatment are discussed.
url http://dx.doi.org/10.1155/2016/3789217
work_keys_str_mv AT xuecai diabeticretinopathyanimalmodelstherapiesandperspectives
AT jamesfmcginnis diabeticretinopathyanimalmodelstherapiesandperspectives
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