Primary drug resistance in a region with high burden of tuberculosis. A critical problem
Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Instituto Nacional de Salud Pública
2015-03-01
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| Series: | Salud Pública de México |
| Subjects: | |
| Online Access: | http://www.saludpublica.mx/index.php/spm/article/view/7414 |
| Summary: | Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3.9% had a multidrug-resistant strain, 15.6% a monoresistant strain and 9.4% a polyresistant strain. Conclusion. Our rate of drug resistant tuberculosis in new cases is very high; this has important clinical implications, since even monoresistance can have a negative impact on the outcome of new cases treated empirically with a six month regimen. |
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| ISSN: | 0036-3634 1606-7916 |