Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques

Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques

Bibliographic Details
Main Authors: Steven Shave, Kris McGuire, Nhan T. Pham, Damian J. Mole, Scott P. Webster, Manfred Auer
Format: Article
Language:English
Published: American Chemical Society 2018-03-01
Series:ACS Omega
Online Access:http://dx.doi.org/10.1021/acsomega.7b02091
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spelling doaj-7c38761819254d0d9d5cb59327531b0a2020-11-25T03:41:08ZengAmerican Chemical SocietyACS Omega2470-13432018-03-01332564256810.1021/acsomega.7b02091Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity TechniquesSteven Shave0Kris McGuire1Nhan T. Pham2Damian J. Mole3Scott P. Webster4Manfred Auer5School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, U.K.‡MRC Centre for Inflammation Research, Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, U.K.School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, U.K.‡MRC Centre for Inflammation Research, Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, U.K.§Centre for Cardiovascular Science, Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, U.K.School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, U.K.http://dx.doi.org/10.1021/acsomega.7b02091
collection DOAJ
language English
format Article
sources DOAJ
author Steven Shave
Kris McGuire
Nhan T. Pham
Damian J. Mole
Scott P. Webster
Manfred Auer
spellingShingle Steven Shave
Kris McGuire
Nhan T. Pham
Damian J. Mole
Scott P. Webster
Manfred Auer
Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
ACS Omega
author_facet Steven Shave
Kris McGuire
Nhan T. Pham
Damian J. Mole
Scott P. Webster
Manfred Auer
author_sort Steven Shave
title Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
title_short Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
title_full Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
title_fullStr Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
title_full_unstemmed Diclofenac Identified as a Kynurenine 3‑Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
title_sort diclofenac identified as a kynurenine 3‑monooxygenase binder and inhibitor by molecular similarity techniques
publisher American Chemical Society
series ACS Omega
issn 2470-1343
publishDate 2018-03-01
url http://dx.doi.org/10.1021/acsomega.7b02091
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AT nhantpham diclofenacidentifiedasakynurenine3monooxygenasebinderandinhibitorbymolecularsimilaritytechniques
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