Overproduction of a kinetic subclass of VLDL-apoB, and direct catabolism of VLDL-apoB in human endogenous hypertriglyceridemia: an analytical model solution of tracer data.

Overproduction of a kinetic subclass of VLDL-apoB, and direct catabolism of VLDL-apoB in human endogenous hypertriglyceridemia: an analytical model solution of tracer data.

To investigate the participation of the major apoprotein involved in triglyceride transport in the pathogenesis of endogenous hypertriglyceridemia, five kinetic studies of apoprotein B were conducted in volunteer normolipidemic subjects and six studies in four patients with endogenous hypertriglycer...

Full description

Bibliographic Details
Main Authors:	R P Eaton, R C Allen, D S Schade
Format:	Article
Language:	English
Published:	Elsevier 1983-10-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520378792

Similar Items

Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2
by: Pia Stillemark-Billton, et al.
Published: (2005-01-01)

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans
by: Berthil H.C.M.T. Prinsen, et al.
Published: (2003-07-01)

In-vivo Metabolismus der VLDL-Apolipoproteine ApoB, ApoCIII und ApoE
by: Dinkel, Regina Elke
Published: (2002)

Increased VLDL-apoB and IDL-apoB production rates in nonlipodystrophic HIV-infected patients on a protease inhibitor-containing regimen
by: Jean Michel Petit, et al.
Published: (2003-09-01)

ApoB-54.8, a truncated apolipoprotein found primarily in VLDL, is associated with a nonsense mutation in the apoB gene and hypobetalipoproteinemia.
by: RD Wagner, et al.
Published: (1991-06-01)

Chronic kidney disease delays VLDL-apoB-100 particle catabolism: potential role of apolipoprotein C-III
by: Doris T. Chan, et al.
Published: (2009-12-01)

Metabolic behavior of hepatic VLDL and plasma LDL apoB-100 in African green monkeys.
by: C A Marzetta, et al.
Published: (1989-03-01)

The N-linked oligosaccharides at the amino terminus of human apoB are important for the assembly and secretion of VLDL
by: Jelena Vukmirica, et al.
Published: (2002-09-01)

Epigallocatechin gallate increases the formation of cytosolic lipid droplets and decreases the secretion of apoB-100 VLDL
by: Lu Li, et al.
Published: (2006-01-01)

Microsomal membrane-associated apoB is the direct precursor of secreted VLDL in primary cultures of rat hepatocytes
by: Abdel-Malek Hebbachi, et al.
Published: (2001-10-01)

Apolipoprotein B signal peptide and apolipoprotein E genotypes as determinants of the hepatic secretion of VLDL apoB in obese men
by: F.M. Riches, et al.
Published: (1998-09-01)

Secretion from cell culture of HDL and VLDL bearing apoB-33 with a large internal deletion
by: M J Wu, et al.
Published: (1997-12-01)

Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway[S]
by: Eric A. Fisher, et al.
Published: (2011-06-01)

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production
by: John S. Millar, et al.
Published: (2006-10-01)

ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice*
by: Zhouji Chen, et al.
Published: (2008-09-01)

Metabolic heterogeneity of low density lipoprotein-apoB production in familial hypercholesterolemia: an analytical model solution of tracer data.
by: R P Eaton, et al.
Published: (1982-07-01)

Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation
by: André J. Tremblay, et al.
Published: (2004-05-01)

Quantitation of apoB-48 and apoB-100 by gel scanning or radio-iodination.
by: D B Zilversmit, et al.
Published: (1989-10-01)

Overexpression ofapoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted micethan in apoB-100-only mice
by: Karin Conde-Knape, et al.
Published: (2004-12-01)

Positive linear correlation between the length of truncated apolipoprotein B and its secretion rate: in vivo studies in human apoB-89, apoB-75, apoB-54.8, and apoB-31 heterozygotes
by: K G Parhofer, et al.
Published: (1996-04-01)

Two apolipoprotein B gene defects in a kindred with hypobetalipoproteinemia, one of which results in a truncated variant, apoB-61, in VLDL and LDL.
by: CR Pullinger, et al.
Published: (1992-05-01)

Regulatory effects of arachidonate 5-lipoxygenase on hepatic microsomal TG transfer protein activity and VLDL-triglyceride and apoB secretion in obese mice
by: Marta López-Parra, et al.
Published: (2008-12-01)

Distinct patterns of lipoproteins with apoB defined by presence of apoE or apoC-III in hypercholesterolemia and hypertriglyceridemia
by: Hannia Campos, et al.
Published: (2001-08-01)

Lovastatin therapy reduces low density lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing the production of apoB-containing lipoproteins: implications for the pathophysiology of apoB production.
by: Y Arad, et al.
Published: (1990-04-01)

Genetic control of hepatic apoB-100 secretion in human apoB transgenic mouse strains
by: Emanuel Voyiaziakis, et al.
Published: (1999-11-01)

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice
by: Myron E. Hinsdale, et al.
Published: (2002-09-01)

Increased proportion of plasma apoB-48 to apoB-100 in non-insulin-dependent diabetic rats: contribution of enhanced apoB mRNA editing in the liver.
by: M Yamane, et al.
Published: (1995-08-01)

The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA2
by: Constantinos C. Tellis, et al.
Published: (2013-12-01)

Hepatic secretion of apoB-100 is impaired in hypobetalipoproteinemic mice with an apoB-38.9-specifying allele
by: Zhouji Chen, et al.
Published: (2004-01-01)

Postprandial changes of apoB-100 and apoB-48 in TG rich lipoproteins in familial combined hyperlipidemia
by: C. Verseyden, et al.
Published: (2002-02-01)

Microsomal triglyceride transfer protein is essential for hepatic secretion of apoB-100 and apoB-48 but not triglyceride
by: To Yuen Hui, et al.
Published: (2002-05-01)

Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice
by: Nancy R. Webb, et al.
Published: (2002-09-01)

Single Nucleotide Polymorphisms of GST CL3, Otrf, FASN, INSIG1, apoVLDLⅡ, and apoB Genes Differentially Expressed in Liver of Taiwan Country Chickens
by: Tzu-Han Chen, et al.
Published: (2008)

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice
by: Emanuel Voyiaziakis, et al.
Published: (1998-02-01)

Inhibition of hepatocyte apoB secretion by naringenin
by: Nica M. Borradaile, et al.
Published: (2002-09-01)

Surface study of apoB1694–1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable
by: Libo Wang, et al.
Published: (2009-07-01)

Quantification of apo[a] and apoB in human atherosclerotic lesions.
by: JM Pepin, et al.
Published: (1991-02-01)

Sources and properties of triglyceride-rich lipoproteins containing apoB-48 and apoB-100 in postprandial blood plasma of patients with primary combined hyperlipidemia
by: J. Kovar, et al.
Published: (2002-07-01)

Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters.
by: J S Cohn, et al.
Published: (1993-12-01)

The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation
by: Mehrpouya B. Mobin, et al.
Published: (2016-09-01)

Cannot write session to /tmp/vufind_sessions/sess_64qh1or1db26j6adn9ccck7i0n