MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS

MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS

The article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive th...

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Main Authors: S. V. Gautier, D. S. Mnatsakanyan
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-09-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
liver transplantation
immune response
calcineurin inhibitor
Online Access:https://journal.transpl.ru/vtio/article/view/194
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spelling doaj-7c10d95134194ceca568b33f6cfaf3d02021-07-29T09:08:27ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov Vestnik Transplantologii i Iskusstvennyh Organov1995-11912012-09-01143778210.15825/1995-1191-2012-3-77-82137MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTSS. V. Gautier0D. S. Mnatsakanyan1Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive therapy protocol choice in pedia- tric liver recipients depending on complications development (nephrotoxicity, arterial hypertension and neuroto- xicity, the high risk of infectious complications, post-transplant proliferative disorders, metabolic and cosmetic side effects) is presented. Different opportunities of early steroid withdrawal, calcineurin inhibitor minimization in pediatric liver allograft recipients are covered.https://journal.transpl.ru/vtio/article/view/194liver transplantationimmune responsecalcineurin inhibitor
collection DOAJ
language Russian
format Article
sources DOAJ
author S. V. Gautier
D. S. Mnatsakanyan
spellingShingle S. V. Gautier
D. S. Mnatsakanyan
MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
Vestnik Transplantologii i Iskusstvennyh Organov
liver transplantation
immune response
calcineurin inhibitor
author_facet S. V. Gautier
D. S. Mnatsakanyan
author_sort S. V. Gautier
title MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
title_short MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
title_full MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
title_fullStr MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
title_full_unstemmed MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
title_sort medicamental immunosupression in early age pediatric liver recipients
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
series Vestnik Transplantologii i Iskusstvennyh Organov
issn 1995-1191
publishDate 2012-09-01
description The article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive therapy protocol choice in pedia- tric liver recipients depending on complications development (nephrotoxicity, arterial hypertension and neuroto- xicity, the high risk of infectious complications, post-transplant proliferative disorders, metabolic and cosmetic side effects) is presented. Different opportunities of early steroid withdrawal, calcineurin inhibitor minimization in pediatric liver allograft recipients are covered.
topic liver transplantation
immune response
calcineurin inhibitor
url https://journal.transpl.ru/vtio/article/view/194
work_keys_str_mv AT svgautier medicamentalimmunosupressioninearlyagepediatricliverrecipients
AT dsmnatsakanyan medicamentalimmunosupressioninearlyagepediatricliverrecipients
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